Teclistamab
Tecvayli (teclistamab) is a bispecific antibody medication used to treat relapsed or refractory multiple myeloma in adults who have received at least four prior lines of therapy. It works by binding to both cancer cells and immune T-cells, enabling the immune system to recognize and destroy myeloma cells.
Tecvayli is a targeted immunotherapy for advanced multiple myeloma that helps the immune system attack cancer cells.
Key facts at a glance
- RxNorm
- 2619434
- Generic
- Tecvayli
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of adult patients with relapsed or refractory multiple myeloma who have received at least four prior lines of therapy, including a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody.
Tecvayli is a bispecific T-cell engager antibody that binds to B-cell maturation antigen (BCMA) on myeloma cells and CD3 on T-cells, bringing them together so the immune system can recognize and kill the cancer cells.
Administered as a subcutaneous injection with a step-up dosing schedule. Due to risk of severe cytokine release syndrome (CRS) and neurotoxicity, it should be prescribed and administered by healthcare professionals experienced in managing these reactions, typically in settings with appropriate supportive care resources.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy