Tedizolid
Tedizolid is an oxazolidinone-class antibiotic used to treat acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). It is available in both intravenous and oral formulations, making it suitable for step-down therapy from IV to oral treatment.
Tedizolid is an antibiotic used to treat serious skin infections caused by gram-positive bacteria including MRSA.
Key facts at a glance
- ATC
- J01XX11
- RxNorm
- 1540825
- Generic
- Tedizolid
- Class
- atc-j01
- Brands
- Sivextro
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- injection, tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Tedizolid is indicated for the treatment of acute bacterial skin and skin structure infections (ABSSSI), including those caused by resistant organisms such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE).
Tedizolid works by binding to the 23S rRNA of the bacterial 50S ribosomal subunit, inhibiting bacterial protein synthesis and preventing bacterial growth. It is bacteriostatic against most organisms.
Tedizolid is generally well-tolerated but may cause side effects including nausea, headache, and diarrhea. Complete the full course of therapy as prescribed. It should be used only when susceptibility testing confirms the infection is susceptible to tedizolid. May interact with serotonergic medications; use with caution in patients on concurrent serotonergic agents.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy