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Aliskiren and Hydrochlorothiazide

Published: August 9, 2026Updated: August 9, 2026

Tekturna HCT is a combination prescription medication used to treat high blood pressure (hypertension). It contains two active ingredients that work together: aliskiren, a direct renin inhibitor that reduces the production of a hormone that raises blood pressure, and hydrochlorothiazide, a diuretic that helps remove excess fluid from the body. This combination is typically prescribed when single-agent therapy is insufficient for blood pressure control.

Quick summary

Tekturna HCT is a combination blood pressure medication containing a renin inhibitor and diuretic for treating hypertension.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 9, 2026Editorial policy

Key facts at a glance

RxNorm
1430137
Generic
Tekturna Hct
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Tekturna HCT is indicated for the treatment of hypertension (high blood pressure) in patients who require combination therapy to achieve adequate blood pressure control. It may be used as initial therapy or in patients already taking the individual components.

Aliskiren, a direct renin inhibitor, blocks the activity of renin, an enzyme that initiates the renin-angiotensin-aldosterone system (RAAS), a hormone cascade that contributes to high blood pressure. Hydrochlorothiazide is a thiazide diuretic that promotes water and sodium excretion, reducing fluid volume and complementing the blood pressure-lowering effect of aliskiren.

Tekturna HCT is not recommended during pregnancy due to potential harm to the fetus. Common side effects may include dizziness, headache, and electrolyte abnormalities. Patients should inform their healthcare provider of all medications and supplements they are taking, as drug interactions can occur. Regular monitoring of blood pressure, kidney function, and electrolytes may be necessary during treatment.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy