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Telmisartan

Published: July 26, 2026Updated: July 26, 2026

Telmisartan is an angiotensin II receptor blocker (ARB) used primarily to treat high blood pressure. It works by blocking the action of angiotensin II, a potent vasoconstrictor, allowing blood vessels to relax and widen, which lowers blood pressure and reduces strain on the heart.

Quick summary

Telmisartan is a blood pressure medication that relaxes blood vessels by blocking angiotensin II, a hormone that causes vasoconstriction.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy
BOXED WARNING

This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.

Key facts at a glance

ATC
C09CA07
RxNorm
73494
Generic
Telmisartan
Class
atc-c09
Brands
Twynsta, Semintra, Micardis, Widaplik, Micardis-HCT
Availability
rx
Lactation
unknown
Routes
oral
Forms
tablet, solution
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dosage and administration

adult (standard)tablet
Usual dose
40-80mg once daily
Maximum
consult physician
Frequency
once daily
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
pediatric (standard)tablet
Usual dose
1mg/kg once daily (not routinely recommended)
Maximum
consult physician
Frequency
once daily
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
geriatric (standard)tablet
Usual dose
40mg once daily
Maximum
consult physician
Frequency
once daily
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard

Overdose information

Important overdose information
Toxic dose: Single dose that may cause serious toxicity - doses up to 640mg have been reported without fatal outcome, but higher doses may cause significant hypotension
Chronic overdose: Excessive hypotension from accumulation due to impaired renal function or drug interactions
Immediate actions
Monitor vital signs, establish IV access, administer IV fluids, position patient supine with legs elevated
Antidote
No specific antidote exists(Supportive care is primary treatment; effectiveness depends on timely intervention)
Poison Control: 1-800-222-1222

Special Populations

9 groups
⚠

pregnancy

first trimester
caution
FDA Category
C
Dose Adjustment

avoid if possible

Key Recommendations

avoid use during pregnancy unless benefits outweigh risks; consider alternative antihypertensives

Monitor

regular fetal monitoring including ultrasound

Use with caution and monitor for adverse effects.

✗

pregnancy

second third trimester
unsafe
FDA Category
D
Dose Adjustment

discontinue immediately if pregnancy detected

Key Recommendations

contraindicated in second and third trimester due to high risk of fetal toxicity

Monitor

close fetal monitoring for renal function and amniotic fluid volume

Use of this medication in this population requires careful consideration of risks and benefits.

✗

lactation

breastfeeding
unsafe
FDA Category
N
Dose Adjustment

not recommended

Key Recommendations

telmisartan is excreted in breast milk; use alternative antihypertensive or discontinue breastfeeding

Monitor

monitor infant for hypotension

Use of this medication in this population requires careful consideration of risks and benefits.

⚠

geriatric

elderly
caution
FDA Category
N
Dose Adjustment

start at lower dose (20mg daily)

Key Recommendations

use with caution due to increased sensitivity to hypotensive effects; monitor renal function closely

Monitor

regular blood pressure monitoring, renal function tests, and electrolyte monitoring

Use with caution and monitor for adverse effects.

?

pediatric_age

children adolescents
unknown
FDA Category
N
Dose Adjustment

not established for pediatric population

Key Recommendations

safety and efficacy not established in children and adolescents; limited data available

Monitor

blood pressure and renal function monitoring if used

⚠

renal_impairment

mild moderate
caution
FDA Category
N
Dose Adjustment

no initial dose adjustment needed; monitor closely

Key Recommendations

use with caution; may cause reversible worsening of renal function; monitor serum creatinine

Monitor

regular monitoring of renal function (creatinine, BUN) and potassium levels

Use with caution and monitor for adverse effects.

⚠

renal_impairment

severe
caution
FDA Category
N
Dose Adjustment

use lower dose, consider reduced frequency

Key Recommendations

use with extreme caution; avoid in bilateral renal artery stenosis

Monitor

frequent renal function monitoring, potassium and electrolyte checks

Use with caution and monitor for adverse effects.

⚠

hepatic_impairment

mild moderate
caution
FDA Category
N
Dose Adjustment

dose reduction may be required

Key Recommendations

use with caution; telmisartan is highly protein bound and metabolized by liver

Monitor

monitor liver function tests and blood pressure

Use with caution and monitor for adverse effects.

⚠

hepatic_impairment

severe
caution
FDA Category
N
Dose Adjustment

use lowest effective dose

Key Recommendations

use with caution in severe hepatic impairment; consider alternative therapy

Monitor

close monitoring of liver function and blood pressure

Use with caution and monitor for adverse effects.

Statistics and clinical data

prescribingFDA
2023

FDA Approval Year

Value:1998

FDA approval year for Telmisartan (Micardis)

drug_classWHO
2023

Drug class

Value:Angiotensin II receptor blocker (ARB)

Telmisartan belongs to the ARB class of antihypertensive medications

usageMedical guidelines
2023

Primary indications

Value:Hypertension, heart failure, cardiovascular risk reduction

Main therapeutic uses of Telmisartan

prescribingFDA
2023

Brand names

Value:Micardis, Twynsta, Semintra, Widaplik, Micardis-HCT

Common brand names for Telmisartan

Treatment of essential hypertension (high blood pressure) in adults. May also be used to reduce cardiovascular events in patients at high risk or with established cardiovascular disease.

Telmisartan blocks angiotensin II type 1 (AT1) receptors. Angiotensin II normally causes vasoconstriction and stimulates aldosterone release, leading to increased blood pressure. By blocking this receptor, telmisartan produces vasodilation, reduces sodium and water retention, and lowers blood pressure.

May cause dizziness or lightheadedness, especially when starting treatment. Avoid use during pregnancy as it can cause fetal harm. Patients with bilateral renal artery stenosis should not use this medication. May interact with potassium-sparing diuretics and NSAIDs. Blood pressure effects may take 2-4 weeks to fully develop.

Contraindications

Conditions and patient states where this medication should be avoided or used with caution.

Do not use (1)

ABSOLUTEhypersensitivity

Known allergy to this medication or its components

Use caution (1)

RELATIVEpregnancy

Consult healthcare provider for benefits vs risks assessment

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy