Trimeprazine/Pyrilamine
Temaril-P is a prescription veterinary medication for dogs that combines an antihistamine (trimeprazine) with a corticosteroid (prednisolone) to provide dual relief from itching and inflammation associated with allergic skin conditions. This combination medication targets both the histamine response and inflammatory processes to address pruritus (itching), hot spots, and dermatitis caused by allergies.
Temaril-P is a veterinary antihistamine-steroid combination used to treat itching and skin inflammation in dogs.
Key facts at a glance
- RxNorm
- 897060
- Generic
- Temaril-P
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temaril-P is used in dogs to relieve itching, scratching, and inflammation caused by allergic skin conditions, including atopic dermatitis, allergic dermatitis, and hot spots. It addresses both environmental and seasonal allergies that cause skin irritation.
Temaril-P combines trimeprazine, an antihistamine with sedative properties that blocks histamine receptors and reduces itching, with prednisolone, a corticosteroid that suppresses inflammatory responses and the immune system's reaction to allergens. Together, they provide both antipruritic and anti-inflammatory effects.
Temaril-P is for veterinary use only and must be prescribed by a veterinarian. Common side effects include drowsiness, increased thirst, appetite, and urination. Long-term use should be avoided due to risks associated with corticosteroid use. It should not be used in pregnant animals or dogs with certain infections. Dosage must be carefully followed as directed by a veterinarian.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy