Temozolomide
Temodar (temozolomide) is an oral alkylating agent chemotherapy medication used to treat certain types of brain tumors, including newly diagnosed glioblastoma multiforme and recurrent anaplastic astrocytoma. It works by damaging the DNA of cancer cells, preventing them from multiplying and growing. This medication is typically prescribed by oncologists specializing in neuro-oncology and is often used in combination with radiation therapy for newly diagnosed brain cancer patients.
Temodar is a chemotherapy drug used to treat specific brain tumors by damaging cancer cell DNA to stop tumor growth.
Key facts at a glance
- RxNorm
- 261663
- Generic
- Temodar
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temodar is FDA-approved for treating adults with newly diagnosed glioblastoma multiforme (used with radiation therapy and then as maintenance therapy) and for treating patients with refractory anaplastic astrocytoma that has recurred or progressed after other treatments.
Temodar is an alkylating agent that works by adding alkyl groups to DNA molecules in cancer cells. This DNA damage prevents cancer cells from replicating and eventually leads to cell death. The medication is a prodrug that converts to its active form after administration.
Common side effects include nausea, vomiting, fatigue, and low blood cell counts. It can cause significant bone marrow suppression, requiring regular blood monitoring. Women should avoid pregnancy during treatment as it may harm an unborn baby. Patients should follow storage instructions carefully since capsules should not be opened or chewed.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy