Diethylpropion
Tenuate (diethylpropion) is a brand-name appetite suppressant that was historically prescribed as a short-term treatment for obesity alongside diet and exercise modifications. It belongs to the class of drugs called sympathomimetic amines, which work by reducing hunger signals in the brain to support weight loss efforts.
Tenuate is an appetite suppressant previously used short-term for weight management in obese patients.
Key facts at a glance
- RxNorm
- 220215
- Generic
- Tenuate
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Tenuate was prescribed for short-term weight management in patients with obesity, typically as part of a comprehensive plan including dietary changes, exercise, and behavioral modifications. It was generally intended for patients whose obesity posed health risks.
As a sympathomimetic amine, Tenuate stimulates the central nervous system to decrease appetite by affecting neurotransmitters in the brain that control hunger. This leads to reduced food intake and supports weight loss efforts when combined with lifestyle changes.
This medication has been discontinued in many countries, including the United States, due to safety concerns related to cardiovascular effects. It should never be used without explicit physician guidance. Common side effects may include increased heart rate, blood pressure elevation, insomnia, and dry mouth. Patients with a history of heart disease, uncontrolled hypertension, or substance abuse should not use this medication. Use was typically limited to a few weeks due to potential for dependence.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy