Thiotepa
Tepadina is the brand name for thiotepa, a chemotherapy medication classified as an alkylating agent. It works by interfering with DNA function in cancer cells, preventing their growth and division. This medication is used to treat various cancers including certain types of breast cancer, ovarian cancer, and bladder cancer, and may also be used as part of conditioning regimens prior to bone marrow transplantation.
Tepadina (thiotepa) is a chemotherapy drug used to treat certain cancers by interfering with cancer cell DNA.
Key facts at a glance
- RxNorm
- 1366537
- Generic
- Tepadina
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Tepadina is used to treat various solid tumors and hematologic malignancies, including breast cancer, ovarian cancer, bladder cancer, and lymphomas. It is also used as part of conditioning regimens prior to hematopoietic stem cell transplantation.
Thiotepa is an alkylating agent that works by transferring alkyl groups to DNA, causing cross-linking of DNA strands. This interferes with DNA replication and transcription, ultimately preventing cancer cells from dividing and leading to cell death.
Tepadina is a cytotoxic medication requiring special handling precautions by healthcare providers. Common side effects include bone marrow suppression (low blood counts), nausea, vomiting, and increased risk of infections. Regular blood count monitoring is essential during treatment. Patients should discuss fertility preservation options with their healthcare team prior to treatment, as the drug may affect fertility.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy