Tetrahydrozoline
Tetrahydrozoline is a topical vasoconstrictor medication used to relieve nasal congestion and eye redness. It works by constricting blood vessels in the nasal passages or eyes, reducing swelling and congestion. This medication is available over-the-counter in nasal spray and eye drop formulations for temporary relief of congestion or red, irritated eyes.
Tetrahydrozoline is a topical decongestant that temporarily relieves nasal congestion and eye redness by constricting blood vessels.
Key facts at a glance
- ATC
- R01AA06
- RxNorm
- 10379
- Generic
- Tetrahydrozoline
- Class
- atc-r01
- Brands
- Optigene, Visine, Altazine
- Availability
- otc
- Pregnancy
- C
- Lactation
- caution
- Half-life (h)
- 5
- Onset (min)
- 5
- Duration (h)
- 6
- Routes
- ophthalmic, nasal
- Forms
- ophthalmic solution, nasal spray, drops
- Regions
- United States, Canada, European Union, United Kingdom, Australia
- Monitoring
- blood pressure, heart rate
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of nasal congestion due to colds, allergies, or sinusitis; relief of eye redness and irritation due to minor eye irritations; may also be used for nasopharyngeal congestion.
Acts as an alpha-adrenergic agonist, causing vasoconstriction of blood vessels in the nasal mucosa or conjunctiva, which reduces swelling, congestion, and redness in the applied area.
Should not be used for more than 3-5 days consecutively to avoid rebound congestion or dependency. Avoid touching dropper tip to prevent contamination. Consult a doctor before use if pregnant, breastfeeding, or taking other medications. Not recommended for children without medical supervision.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy