Tezepelumab
Tezspire (tezepelumab) is a biologic medication used as an add-on maintenance therapy for severe asthma in patients 12 years and older. It works by targeting thymic stromal lymphopoietin (TSLP), an inflammatory protein involved in asthma pathophysiology, to help reduce airway inflammation and decrease asthma exacerbations when standard therapies are insufficient.
Tezspire is a biologic injection used with other asthma medicines to help control severe asthma in patients 12 years and older.
Key facts at a glance
- RxNorm
- 2587796
- Generic
- Tezspire
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Severe asthma in patients 12 years and older as an add-on maintenance therapy when standard asthma treatments do not provide adequate control.
Tezepelumab is a monoclonal antibody that blocks TSLP, an inflammatory cytokine that initiates and sustains airway inflammation in asthma, thereby reducing inflammation and asthma exacerbations.
Administered as a subcutaneous injection every 4 weeks. Not for acute asthma attacks or sudden breathing problems. Patients should be monitored for potential allergic reactions and infections during treatment.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy