Silver Sulfadiazine
Thermazene is a topical antibiotic cream containing silver sulfadiazine, used primarily in burn wound care. It is applied to burned skin to help prevent and treat bacterial infections that commonly occur in burn injuries.
Thermazene is a topical silver-based antibiotic cream used to prevent and treat infections in burn wounds.
Key facts at a glance
- RxNorm
- 220297
- Generic
- Thermazene
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Thermazene is indicated for the prevention and treatment of bacterial infections in second- and third-degree burn wounds. It is commonly used in hospital settings and for outpatient burn wound management.
Thermazene contains silver sulfadiazine, a sulfonamide antibiotic that works by inhibiting bacterial growth on the surface of the skin. The silver component provides broad-spectrum antimicrobial activity against various bacteria and some fungi commonly found in burn wounds.
Thermazene is for external use only and should be applied as a thin layer to the affected area. Possible side effects may include skin irritation, allergic reactions, or in rare cases, blood abnormalities with prolonged use. Patients with sulfonamide allergies should not use this medication. Medical supervision is recommended for appropriate wound care and infection monitoring.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 9, 2026. · Read our editorial policy