Thiethylperazine
Thiethylperazine is a phenothiazine-class antiemetic medication primarily used to prevent and treat nausea and vomiting. It is also prescribed for vertigo and motion sickness-related symptoms. The medication works by blocking dopamine receptors in the brain's chemoreceptor trigger zone, reducing nausea signals.
Thiethylperazine is an antiemetic used to treat nausea, vomiting, and vertigo by blocking dopamine activity in the brain.
Key facts at a glance
- ATC
- R06AD03
- RxNorm
- 10471
- Generic
- Thiethylperazine
- Class
- atc-r06a
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment and prevention of nausea and vomiting from various causes including post-operative, chemotherapy-induced, and vestibular-related (vertigo, motion sickness). May also be used as preoperative medication.
Functions as a dopamine D2 receptor antagonist in the chemoreceptor trigger zone of the brain, blocking emetic signals. Also exhibits anticholinergic and antihistamine properties that contribute to its antiemetic effect.
May cause drowsiness and sedation; avoid driving until familiar with effects. Contraindicated in patients with Parkinson's disease, prolactin-dependent tumors, or severe CNS depression. Should be used with caution in elderly patients due to increased risk of extrapyramidal side effects. Not recommended during pregnancy unless clearly necessary.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy