Thiocolchicoside
Thiocolchicoside is a muscle relaxant medication derived from colchicine, used to treat acute musculoskeletal conditions involving painful muscle spasms. It acts on GABA receptors in the central nervous system and also possesses anti-inflammatory properties, making it particularly useful for spinal disorders and musculoskeletal pain. The medication is available in both oral and injectable formulations.
Thiocolchicoside is a centrally-acting muscle relaxant used to relieve acute muscle spasms and associated pain from musculoskeletal conditions.
Key facts at a glance
- ATC
- M03BX05
- RxNorm
- 38085
- Generic
- Thiocolchicoside
- Class
- atc-m03b
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- capsule
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Thiocolchicoside is prescribed for acute musculoskeletal pain associated with muscle spasms, including conditions such as low back pain (lumbago), cervical pain, torticollis, and other spinal disorders. It is also used in rehabilitation programs following orthopedic surgery or trauma.
Thiocolchicoside acts primarily on the GABAergic system in the central nervous system, modulating GABA-A receptors to reduce muscle hyperactivity. Additionally, it exhibits anti-inflammatory and analgesic properties, providing relief from both pain and inflammation associated with muscle spasms.
Thiocolchicoside should be used for short-term treatment only, typically not exceeding 5-7 days. It may cause drowsiness or dizziness, so patients should avoid operating machinery or driving until they know how the medication affects them. Use is contraindicated in patients with hypersensitivity, pregnancy, and during breastfeeding. Alcohol may enhance sedative effects and should be avoided.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy