Thonzylamine
Thonzylamine is a first-generation antihistamine medication classified as an antipruritic. It works by blocking histamine H1 receptors to help relieve itching and allergic skin reactions. This medication has largely fallen out of common clinical use in favor of newer antihistamines with improved safety profiles.
Thonzylamine is an older antihistamine used to relieve itching and allergic skin conditions by blocking histamine receptors.
Key facts at a glance
- ATC
- D04AA01
- RxNorm
- 1360721
- Generic
- Thonzylamine
- Class
- atc-d04
- Brands
- Nasopen PE
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used to relieve itching and mild allergic skin reactions, including urticaria (hives) and other histamine-mediated dermatological conditions.
Functions as an H1 receptor antagonist, blocking histamine from binding to its receptors and reducing allergic symptoms such as itching and inflammation.
As a first-generation antihistamine, it may cause drowsiness and sedation. Use has declined significantly with the development of newer, less sedating antihistamines. Should be used with caution in patients with glaucoma, urinary retention, or benign prostatic hyperplasia.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy