Ticlopidine
Ticlopidine is an antiplatelet medication that helps prevent blood clots from forming by inhibiting platelet aggregation. It was historically used to reduce the risk of stroke and heart attack in patients with established cardiovascular disease, though it has largely been replaced by newer agents with better safety profiles.
Ticlopidine is an antiplatelet drug used to prevent blood clots in patients at risk for stroke or heart attack, though it requires careful monitoring due to potential serious blood-related side effects.
Key facts at a glance
- ATC
- B01AC05
- RxNorm
- 10594
- Generic
- Ticlopidine
- Class
- atc-b01
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Ticlopidine is used to reduce the risk of stroke in patients who have experienced a prior stroke or transient ischemic attack (TIA), and to prevent clot formation in patients who have undergone coronary stent placement. It may also be used as an alternative antiplatelet therapy for patients intolerant of aspirin.
Ticlopidine belongs to the thienopyridine class of antiplatelet agents. It works by irreversibly inhibiting the ADP receptor on platelets, which prevents platelet activation and aggregation. This reduces the blood's ability to form harmful clots that could lead to stroke or other cardiovascular events.
Ticlopidine requires regular blood monitoring, particularly during the first three months of therapy, due to the risk of neutropenia and thrombotic thrombocytopenic purpusa (TTP). Common side effects include diarrhea, nausea, and dyspepsia. Due to its significant safety concerns, clopidogrel is typically preferred over ticlopidine in clinical practice.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy