Tikosyn
Tikosyn is a prescription antiarrhythmic medication containing dofetilide, used to treat irregular heartbeats such as atrial fibrillation and atrial flutter. It works by blocking potassium channels in the heart to help maintain a normal heart rhythm. Due to the risk of serious side effects, it must be initiated in a hospital setting with cardiac monitoring.
Tikosyn is an antiarrhythmic drug used to treat atrial fibrillation and flutter, requiring careful hospital-based initiation due to potential heart rhythm risks.
Key facts at a glance
- RxNorm
- 261672
- Generic
- Tikosyn
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of atrial fibrillation and atrial flutter to maintain normal heart rhythm. Typically prescribed when other medications have not been effective.
Class III antiarrhythmic that blocks potassium channels (IKr) in cardiac tissue, which prolongs the action potential duration and refractory period, helping to prevent irregular heart rhythms.
Must be initiated in a hospital with continuous ECG monitoring for at least 3 days. Can cause serious ventricular arrhythmias (Torsades de Pointes). Requires regular kidney function monitoring and avoided with certain medications. Only available through a restricted distribution program.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy