Tiludronic Acid
Tiludronic acid is a bisphosphonate medication used to treat Paget's disease of bone, a chronic disorder that causes abnormal bone destruction and regrowth. It works by inhibiting the activity of osteoclasts, the cells responsible for bone breakdown, helping to normalize bone turnover and reduce bone pain.
Tiludronic acid is a bisphosphonate used to treat Paget's disease by reducing abnormal bone breakdown.
Key facts at a glance
- ATC
- M05BA05
- RxNorm
- 11476
- Generic
- Tiludronic Acid
- Class
- atc-m05
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primarily used to treat Paget's disease of bone in patients with symptomatic disease or those at risk for complications. May be considered in some cases of hypercalcemia of malignancy.
As a bisphosphonate, tiludronic acid inhibits osteoclast-mediated bone resorption by binding to bone mineral and being taken up by osteoclasts, where it disrupts their normal function and promotes apoptosis.
Take on an empty stomach with plain water; remain upright for at least 30 minutes after dosing. Avoid taking with calcium, antacids, or mineral supplements within 2 hours. Common side effects include gastrointestinal symptoms. Rarely may cause osteonecrosis of the jaw or atypical femoral fractures with long-term use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy