Tioconazole
Tioconazole is an antifungal medication used to treat various fungal infections, including vaginal yeast infections, athlete's foot, ringworm, and other skin conditions caused by susceptible fungi. It works by inhibiting the growth of fungi, allowing the body's natural defenses to eliminate the infection.
Topical antifungal used to treat yeast infections, athlete's foot, ringworm, and related fungal skin conditions.
Key facts at a glance
- ATC
- d01a
- RxNorm
- unknown
- Generic
- Tioconazole
- Class
- atc-d01a
- Brands
- Monistat Simple Therapy, Vagistat-1
- Availability
- otc
- Pregnancy
- B
- Lactation
- caution
- Half-life (h)
- 30
- Onset (min)
- 0
- Duration (h)
- 0
- Routes
- vaginal
- Forms
- vaginal cream, vaginal suppository
- Regions
- United States, Canada, United Kingdom, Australia
- Monitoring
- local irritation, allergic reactions, infection persistence
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of vulvovaginal candidiasis (vaginal yeast infection), tinea pedis (athlete's foot), tinea corporis (ringworm), tinea cruris (jock itch), and other cutaneous fungal infections. Also used for fungal nail infections in some formulations.
Tioconazole is an imidazole antifungal that inhibits the synthesis of ergosterol, a critical component of the fungal cell membrane. By disrupting membrane integrity, it prevents fungal growth and replication.
For topical or vaginal use only; avoid contact with eyes. Not for oral or intravenous use. May cause local irritation, burning, or redness. Inform your doctor if symptoms don't improve after treatment course. Pregnancy category C; consult healthcare provider before use if pregnant or breastfeeding.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy