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Tobi

Published: July 26, 2026Updated: August 25, 2026

Tobi is an inhaled antibiotic solution containing tobramycin, an aminoglycoside medication. It is specifically indicated for managing chronic Pseudomonas aeruginosa lung infections in cystic fibrosis patients aged 6 years and older. The medication is administered twice daily using a nebulizer to deliver the drug directly to the lungs.

Quick summary

Tobi is an inhaled antibiotic used to treat Pseudomonas lung infections in cystic fibrosis patients.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
220329
Generic
Tobi
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Tobi is prescribed for the management of chronic Pseudomonas aeruginosa infections in the lungs of cystic fibrosis patients. It is not used for treating other bacterial infections or conditions unrelated to cystic fibrosis.

Tobramycin, the active ingredient, is an aminoglycoside antibiotic that works by inhibiting bacterial protein synthesis. When inhaled, it is delivered directly to the airways where it accumulates in bacterial cells and disrupts their ability to produce proteins essential for survival, effectively killing or stopping the growth of Pseudomonas aeruginosa.

Tobi should be used exactly as prescribed by a healthcare provider. Common side effects may include voice changes, sore throat, and cough. Patients with kidney problems, hearing problems, or neuromuscular diseases should inform their doctor before use. Bronchospasm can occur in some patients; a test dose may be recommended initially. Tobi capsules are for inhalation use only and should not be injected or swallowed.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy