Tocainide
Tocainide is an antiarrhythmic medication classified as a Class IB agent that works by blocking sodium channels in cardiac tissue. It was primarily used to treat ventricular arrhythmias, including ventricular premature contractions and tachycardia.
Tocainide is a Class IB antiarrhythmic used to manage certain ventricular heart rhythm disorders.
Key facts at a glance
- ATC
- C01BB03
- RxNorm
- 42359
- Generic
- Tocainide
- Class
- atc-c01
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used for the treatment of symptomatic ventricular arrhythmias, including ventricular premature contractions and ventricular tachycardia. It was one of the few oral antiarrhythmics available for long-term management of these conditions.
Tocainide works by blocking voltage-gated sodium channels in cardiac myocytes, which stabilizes cell membranes and reduces the rate of depolarization. This decreases the automaticity of cardiac tissue and helps restore normal rhythm.
Like other Class I antiarrhythmics, tocainide may proarrhythmic effects in some patients. It requires careful patient selection and monitoring. This medication is no longer widely available in many countries due to concerns about side effects and the availability of safer alternatives.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy