Tolazamide
Tolazamide is a first-generation sulfonylurea that treats type 2 diabetes by stimulating the pancreas to release more insulin, helping to lower blood glucose levels.
Tolazamide is an oral diabetes medication that helps control blood sugar in type 2 diabetes by stimulating insulin release from the pancreas.
Key facts at a glance
- ATC
- A10BB05
- RxNorm
- 10633
- Generic
- Tolazamide
- Class
- atc-a10
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Tolazamide is used to treat type 2 diabetes mellitus in adults when blood glucose levels cannot be adequately controlled through diet, exercise, and weight management alone.
As a sulfonylurea, tolazamide stimulates insulin secretion from functioning pancreatic beta cells by blocking ATP-sensitive potassium channels, leading to increased insulin release and lowered blood glucose levels.
May cause hypoglycemia, particularly in elderly, malnourished, or renally/hepatically impaired patients. Effectiveness requires functioning pancreatic beta cells. Should be used alongside diet and exercise. Risk of weight gain. May interact with other medications affecting blood glucose.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy