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Tolfenamic Acid

Published: July 26, 2026Updated: August 25, 2026

Tolfenamic Acid is a non-steroidal anti-inflammatory drug (NSAID) belonging to the anthranilic acid class. It is used to treat pain, inflammation, and fever, with particular effectiveness for acute migraine attacks in adults. The medication works by inhibiting cyclooxygenase enzymes, thereby reducing the production of prostaglandins responsible for pain and inflammatory responses.

Quick summary

Tolfenamic Acid is an NSAID used for pain relief, inflammation reduction, and migraine treatment.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

ATC
M01AG02
RxNorm
38377
Generic
Tolfenamic Acid
Class
atc-m01
Brands
—
Availability
rx
Lactation
unknown
Routes
oral
Forms
tablet
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of acute migraine attacks, mild to moderate pain, fever, and inflammatory conditions such as rheumatoid arthritis and osteoarthritis.

Acts as a non-selective inhibitor of cyclooxygenase (COX) enzymes, blocking the synthesis of prostaglandins that mediate pain, inflammation, and fever.

Like other NSAIDs, it may cause gastrointestinal irritation, ulcers, or bleeding. Contraindicated in patients with active peptic ulcers, severe kidney or liver impairment, and should be avoided in late pregnancy. Use with caution in patients with cardiovascular disease or history of gastrointestinal problems.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy