Tolmetin
Tolmetin is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, swelling, and joint stiffness caused by conditions such as osteoarthritis and rheumatoid arthritis. It works by blocking substances in the body that cause inflammation and pain.
Tolmetin is an NSAID used to treat pain and inflammation from arthritis conditions.
This medication carries a boxed (black box) warning — the strongest type of FDA warning. Review the full prescribing information before use.
Key facts at a glance
- ATC
- M01AB03
- RxNorm
- 10636
- Generic
- Tolmetin
- Class
- atc-m01
- Brands
- Tolectin 600, Tolectin DS
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet, capsule
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. May also be used for acute gouty arthritis and other inflammatory conditions involving pain and swelling.
Tolmetin inhibits cyclooxygenase (COX) enzymes, reducing the production of prostaglandins that cause inflammation, pain, and fever.
May increase risk of serious cardiovascular events, GI bleeding, and renal impairment. Contraindicated in perioperative pain during coronary artery bypass graft surgery. Use with caution in patients with history of peptic ulcer disease, hypertension, or heart failure. Avoid during late pregnancy.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy