Skip to content

Tolsura

Published: July 26, 2026Updated: August 25, 2026

Tolsura is a brand-name prescription antifungal medication containing itraconazole, used to treat certain serious fungal infections such as blastomycosis and histoplasmosis. It works by inhibiting the growth of fungi that cause infection. This medication is typically prescribed when fungal infections are widespread or affect internal organs.

Quick summary

Tolsura is a prescription antifungal used to treat serious fungal infections like blastomycosis and histoplasmosis.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
2106643
Generic
Tolsura
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Tolsura is used to treat blastomycosis (infection caused by Blastomyces fungus) and histoplasmosis (infection caused by Histoplasma fungus), which can affect the lungs and other organs. It may also be used for other fungal infections as determined by a healthcare provider.

Tolsura contains itraconazole, an azole antifungal that works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes. This disruption weakens the fungal cell wall, preventing the fungus from growing and spreading.

Tolsura should not be used by patients with heart failure. It has numerous drug interactions and should be taken with food for optimal absorption. Liver function monitoring may be needed during treatment. Pregnant women should avoid this medication. Always complete the full course of treatment as prescribed.

Official drug label

WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy