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Toposar

Published: July 26, 2026Updated: August 25, 2026

Toposar (etoposide) is a prescription chemotherapy medication used to treat various types of cancer, including testicular cancer, small cell lung cancer, and certain lymphomas. It works by interfering with cancer cell DNA replication, ultimately leading to cancer cell death. This medication is typically administered under the supervision of an oncologist as part of combination chemotherapy regimens.

Quick summary

Toposar is a chemotherapy drug used to treat several types of cancer by damaging cancer cell DNA to prevent their growth and division.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
220347
Generic
Toposar
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Toposar is used to treat testicular cancer that has not responded to other treatments, small cell lung cancer, Hodgkin's lymphoma, non-Hodgkin's lymphoma, and acute myeloid leukemia. It may also be used for other cancers as determined by an oncologist.

Toposar contains etoposide, which inhibits an enzyme called topoisomerase II that is essential for DNA replication in cells. By blocking this enzyme, it causes DNA strand breaks that prevent cancer cells from dividing and multiplying, ultimately leading to cell death.

Toposar is administered intravenously by healthcare professionals and requires regular monitoring of blood counts and organ function. Common side effects include bone marrow suppression, hair loss, nausea, and fatigue. Patients should avoid live vaccines during treatment and inform their doctor of all medications, as drug interactions can occur. Pregnant women should not handle this medication due to potential harm to the fetus.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy