Torisel
Torisel (temsirolimus) is an mTOR inhibitor used to treat advanced renal cell carcinoma and mantle cell lymphoma. It works by blocking a specific protein that regulates cancer cell growth and division, slowing tumor progression.
Torisel is an anticancer medication used to treat certain types of kidney cancer and lymphoma by inhibiting cancer cell growth.
Key facts at a glance
- RxNorm
- 723805
- Generic
- Torisel
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Torisel is FDA-approved for the treatment of advanced renal cell carcinoma (kidney cancer) and relapsed or refractory mantle cell lymphoma, a type of non-Hodgkin lymphoma.
Torisel is a mammalian target of rapamycin (mTOR) inhibitor that binds to a specific intracellular protein (FKBP-12), forming a complex that blocks mTOR kinase activity. This inhibition disrupts signaling pathways that promote tumor cell growth, proliferation, and angiogenesis.
Torisel is administered as an intravenous infusion, typically once weekly. Common side effects include rash, mouth sores, nausea, weakness, and metabolic changes. Patients should be monitored for hypersensitivity reactions during infusion, as well as for elevated blood glucose and lipid levels. It may cause immunosuppression and should not be used during pregnancy.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy