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Tosymra

Published: July 26, 2026Updated: August 25, 2026

Tosymra is a brand-name nasal spray medication used for the acute treatment of migraine attacks with or without aura in adults. It delivers the active ingredient sumatriptan directly through the nasal passages for rapid absorption.

Quick summary

Tosymra is a prescription nasal spray used to treat acute migraine headaches in adults.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
2178068
Generic
Tosymra
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Tosymra is indicated for the acute treatment of migraine attacks with or without aura in adult patients. It is not used for migraine prevention and should not be used for cluster headaches or other types of headaches.

Tosymra contains sumatriptan, a selective serotonin receptor agonist (triptan). It works by binding to serotonin receptors in the brain, causing vasoconstriction of cranial blood vessels and reducing inflammation associated with migraine attacks.

Tosymra is available by prescription only and should not be used by patients with certain cardiovascular conditions, uncontrolled hypertension, or who are taking certain other medications. Common side effects may include taste disturbances, nasal discomfort, and dizziness. Patients should discuss their complete medical history with their healthcare provider before use.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy