Tovorafenib
Tovorafenib is a Type II RAF kinase inhibitor used to treat cancers harboring BRAF mutations, particularly the BRAF V600E mutation. It works by targeting and inhibiting mutant BRAF V600E, wild-type BRAF, and wild-type CRAF kinases, which are involved in cancer cell proliferation and survival.
Targeted therapy that inhibits RAF kinases to treat BRAF-mutated cancers.
Key facts at a glance
- ATC
- L01EC04
- RxNorm
- 2682434
- Generic
- Tovorafenib
- Class
- atc-l01
- Brands
- Ojemda
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- suspension, tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
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Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Tovorafenib is indicated for the treatment of cancers with BRAF V600E and V600D mutations, including melanoma and other solid tumors harboring these genetic alterations.
As a Type II RAF kinase inhibitor, tovorafenib blocks the activity of mutant BRAF V600E, wild-type BRAF, and wild-type CRAF kinases, disrupting signaling pathways that promote tumor cell growth and survival.
As a targeted therapy, tovorafenib requires BRAF mutation testing prior to treatment. Common adverse effects may include skin reactions, fatigue, and liver enzyme elevations. Patients should be monitored for skin toxicity and other treatment-related complications.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
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Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy