Tretten
Tretten is a recombinant coagulation factor XIII A-subunit used for routine preventive treatment of bleeding in patients with congenital factor XIII deficiency. It works by replacing the missing clotting factor to help stabilize blood clots and reduce the risk of spontaneous bleeding episodes.
Tretten is a recombinant factor XIII replacement therapy used to prevent bleeding in patients born with congenital factor XIII deficiency.
Key facts at a glance
- RxNorm
- 1488296
- Generic
- Tretten
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Tretten is indicated for routine prophylactic treatment of bleeding episodes in patients with congenital factor XIII A-subunit deficiency, a rare inherited bleeding disorder.
Tretten contains recombinant human coagulation factor XIII A-subunit, which replaces the deficient endogenous factor XIII. Factor XIII cross-links fibrin to stabilize blood clots and protect them from breakdown, which is essential for proper clot formation and wound healing.
Tretten is administered via intravenous injection by a healthcare professional or trained caregiver. Patients should be monitored for signs of hypersensitivity reactions. This is a specialized treatment available only by prescription and requires proper diagnosis of congenital FXIII deficiency by a hematologist. Treatment is typically given as regular prophylactic doses to maintain adequate factor levels.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy