Trezix
Trezix is a brand-name combination analgesic medication containing acetaminophen, caffeine, and dihydrocodeine. It is typically prescribed for the management of moderate to moderately severe pain when other pain relievers have not been effective. This medication should only be used under the supervision of a healthcare provider due to the presence of an opioid component.
Trezix is a prescription combination pain medication used for moderate to severe pain, containing an opioid component along with acetaminophen and caffeine.
Key facts at a glance
- RxNorm
- 746611
- Generic
- Trezix
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Trezix is indicated for the relief of moderate to moderately severe pain. It is typically considered when other non-opioid analgesics have not provided adequate pain control.
The medication combines three ingredients: acetaminophen provides pain relief and reduces fever, caffeine enhances the analgesic effects and may help constrict blood vessels associated with certain headaches, and dihydrocodeine is an opioid analgesic that works on the central nervous system to alter the body's perception of pain.
Due to the opioid component, Trezix carries risks of dependence, tolerance, and potential for misuse. It should not be combined with alcohol, sedatives, or other CNS depressants. Patients should follow their prescribed dosage exactly and consult their healthcare provider about any history of substance use disorders, liver problems, or breathing conditions before use. This is a prescription-only medication.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy