Trichlormethiazide
Trichlormethiazide is a thiazide diuretic used to treat fluid retention (edema) and high blood pressure. It works by helping the kidneys remove excess salt and water from the body, which reduces the workload on the heart and lowers blood pressure. This medication is typically prescribed for conditions such as heart failure, liver cirrhosis, kidney disorders, and hypertension.
Trichlormethiazide is a thiazide diuretic that removes excess fluid from the body to treat edema and hypertension.
Key facts at a glance
- ATC
- C03AA06
- RxNorm
- 10772
- Generic
- Trichlormethiazide
- Class
- atc-c03
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Trichlormethiazide is used to treat hypertension (high blood pressure) and edema associated with conditions such as congestive heart failure, liver cirrhosis, kidney dysfunction, and corticosteroid or estrogen therapy.
As a thiazide diuretic, trichlormethiazide inhibits the sodium-chloride cotransporter in the distal convoluted tubule of the kidney. This action prevents sodium and chloride reabsorption, leading to increased urinary excretion of sodium, chloride, and water while reducing fluid volume in the body.
Thiazide diuretics may cause electrolyte imbalances, particularly low potassium (hypokalemia), low sodium (hyponatremia), and elevated blood sugar. Patients should have their electrolytes monitored regularly. The medication may increase sun sensitivity, and adequate hydration is important during treatment. It is generally less effective in patients with severely impaired kidney function.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy