Triclofos
Triclofos is a sedative-hypnotic medication primarily used for the short-term treatment of insomnia and as a preoperative sedative to calm patients before procedures. It belongs to the ATC N05 classification of psycholeptic drugs. Triclofos is converted to trichloroethanol in the body, which produces its calming and sleep-inducing effects.
Triclofos is a sedative-hypnotic used to treat insomnia and anxiety before medical procedures.
Key facts at a glance
- ATC
- N05CM07
- RxNorm
- 38610
- Generic
- Triclofos
- Class
- atc-n05
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Triclofos is primarily prescribed for the short-term management of insomnia where sleep initiation is the primary concern. It may also be used as a preoperative sedative to reduce anxiety before surgical or diagnostic procedures. Occasionally, it has been used for sedation in pediatric patients undergoing certain medical examinations.
Triclofos is metabolized in the body to trichloroethanol, which is the active compound responsible for its pharmacological effects. As a sedative-hypnotic, it acts on the central nervous system to produce calming effects and facilitate sleep onset. The exact mechanism of action involves general CNS depression, similar to other hypnotic agents.
Triclofos should be used at the lowest effective dose for the shortest duration possible due to risks of dependence and tolerance. Common side effects may include morning drowsiness, dizziness, and gastrointestinal disturbances. It should be avoided in patients with severe liver or kidney impairment, porphyria, or those with known sensitivity to chloral derivatives. Alcohol should be avoided during treatment as it may enhance sedative effects.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy