Trihexyphenidyl
Trihexyphenidyl is an anticholinergic medication primarily used to treat Parkinson's disease and manage movement disorders caused by certain psychiatric medications. It helps reduce tremors, muscle stiffness, and other symptoms by restoring the natural balance of certain chemical messengers in the brain.
An anticholinergic medication used to treat Parkinson's disease and drug-induced movement disorders.
Key facts at a glance
- ATC
- N04AA01
- RxNorm
- 10811
- Generic
- Trihexyphenidyl
- Class
- atc-n04
- Brands
- —
- Availability
- rx
- Pregnancy
- C
- Lactation
- caution
- Routes
- oral
- Forms
- solution, tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Trihexyphenidyl is used to treat Parkinson's disease, especially in cases with significant tremor or drooling, as well as drug-induced parkinsonism caused by antipsychotic or other medications that can cause extrapyramidal symptoms.
Trihexyphenidyl blocks acetylcholine receptors in the brain, counteracting the overactivity of acetylcholine relative to dopamine. This helps restore the chemical balance and improves muscle control in movement disorders.
Common side effects include dry mouth, blurred vision, constipation, and dizziness. This medication should be used cautiously in elderly patients and those with glaucoma, urinary retention, or digestive blockages. Alcohol and other sedating substances may increase drowsiness.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy