Fenofibric Acid
Trilipix (fenofibric acid) is a fibrate medication used to treat unhealthy lipid levels, including high triglycerides and mixed dyslipidemia. It works by activating PPAR-alpha receptors to help break down fatty substances in the blood and increase HDL ('good') cholesterol. This medication is typically prescribed alongside diet and exercise when lifestyle changes alone are insufficient.
Trilipix is a prescription fibrate that helps lower triglycerides and improve overall cholesterol levels in patients with lipid disorders.
Key facts at a glance
- RxNorm
- 828374
- Generic
- Trilipix
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Trilipix is used to treat hypertriglyceridemia (high triglycerides) and mixed dyslipidemia (unhealthy levels of multiple blood fats including cholesterol and triglycerides). It may be used when diet, exercise, and weight loss have not been adequate.
Trilipix belongs to the fibrate drug class and works by activating peroxisome proliferator-activated receptor alpha (PPARα). This increases the activity of enzymes that break down and remove triglyceride-rich particles from the bloodstream while also modestly increasing HDL cholesterol.
Trilipix is not a substitute for diet and exercise. Common side effects may include headache, back pain, and digestive issues. Patients with liver, gallbladder, or severe kidney disease should use caution. Regular blood tests to monitor liver function and lipid levels are typically recommended during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy