Polyethylene Glycol
Trilyte is a brand-name bowel preparation medication used to cleanse the colon before medical procedures such as colonoscopies, radiologic examinations, or bowel surgeries. It contains a combination of polyethylene glycol and electrolytes that works as an osmotic laxative, drawing water into the intestines to produce watery diarrhea and effectively empty the colon. This medication is prescribed by healthcare providers and requires careful adherence to dosing instructions for optimal results.
Trilyte is a prescription bowel prep solution used to clear the colon before medical procedures like colonoscopy.
Key facts at a glance
- RxNorm
- 763604
- Generic
- Trilyte
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Trilyte is primarily used for bowel cleansing before diagnostic procedures such as colonoscopy, sigmoidoscopy, and barium enema X-rays, as well as before colorectal surgery. It may also be used in certain cases of severe constipation as determined by a healthcare provider.
Trilyte contains polyethylene glycol 3350 along with electrolytes. It works as an osmotic laxative by drawing water into the intestines through osmosis, which softens stool and increases its volume. This stimulates bowel movements and helps flush the entire colon, providing thorough cleansing for medical procedures.
Trilyte must be mixed with water as directed and consumed over several hours. Adequate hydration is essential during use. Patients should follow their doctor's specific instructions regarding diet restrictions before and during prep. This medication should not be used for regular constipation relief. Patients with certain conditions such as bowel obstruction, severe ulcerative colitis, or kidney problems should inform their doctor before use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy