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Hyaluronan

Published: July 26, 2026Updated: August 25, 2026

Trivisc is a brand-name hyaluronic acid injection used to relieve joint pain associated with osteoarthritis. It is administered directly into the knee joint (or occasionally other joints) as a series of injections. This medication is typically prescribed when conservative treatments like over-the-counter pain relievers have not provided adequate relief.

Quick summary

Trivisc is an injectable hyaluronic acid treatment for osteoarthritis joint pain, administered directly into the affected joint.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
2109944
Generic
Trivisc
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Trivisc is indicated for the treatment of osteoarthritis-related joint pain, primarily in the knee. It is generally used when patients have not responded well to conservative treatments such as physical therapy, exercise, or oral pain medications.

Trivisc contains sodium hyaluronate, which supplements the natural hyaluronic acid in joint fluid. This helps restore the viscosity and elasticity of synovial fluid, potentially reducing friction and pain within the joint.

Trivisc is administered as a series of injections directly into the affected joint by a healthcare professional. Side effects may include joint pain, swelling, or stiffness at the injection site. Patients should follow their healthcare provider's dosing schedule and report any unusual symptoms. Safety during pregnancy or breastfeeding has not been established.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy