Trofosfamide
Trofosfamide is an alkylating antineoplastic agent classified under ATC-L01, related to ifosfamide and cyclophosphamide. It is used in the treatment of various malignancies and works by damaging cancer cell DNA to prevent replication and division.
Trofosfamide is a chemotherapy medication used to treat certain cancers by interfering with cancer cell DNA.
Key facts at a glance
- ATC
- L01AA07
- RxNorm
- 38865
- Generic
- Trofosfamide
- Class
- atc-l01
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used in the treatment of various malignant conditions including lymphomas, leukemias, and certain solid tumors. It has been employed in both pediatric and adult oncology settings, particularly in some European countries.
Functions as an alkylating agent that cross-links DNA strands, preventing cancer cell replication and division. It is metabolized in the liver to active metabolites that bind to and damage DNA, inhibiting tumor cell proliferation.
Like other oxazaphosphorine chemotherapy agents, it carries risks including bone marrow suppression, hemorrhagic cystitis, and potential nephrotoxicity. Requires careful monitoring, adequate hydration, and regular blood count assessment during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy