Topiramate
Trokendi is a brand-name extended-release medication containing the active ingredient topiramate. It belongs to the anticonvulsant drug class and is primarily used to treat epilepsy and prevent migraine headaches in adults and certain pediatric patients.
Trokendi is an anticonvulsant medication used for seizure control and migraine prevention.
Key facts at a glance
- RxNorm
- 1436240
- Generic
- Trokendi
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Trokendi is indicated for the treatment of partial-onset seizures and primary generalized tonic-clonic seizures in adults and children 6 years and older, as well as for migraine prophylaxis in adults 18 years and older.
As an extended-release formulation of topiramate, this medication works by multiple mechanisms including blocking sodium channels, enhancing GABA activity, and inhibiting carbonic anhydrase, which helps reduce neuronal excitability and seizure activity.
This medication requires a valid prescription and should not be stopped abruptly. Common side effects may include dizziness, drowsiness, and weight loss. Patients should report any vision changes, kidney stones, or mood changes. Close monitoring is needed for cognitive effects and adequate hydration is recommended to reduce kidney stone risk.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy