Capivasertib
Truqap (capivasertib) is an AKT inhibitor medication used to treat hormone receptor-positive, HER2-negative breast cancer in adults. It works by blocking the PI3K/AKT signaling pathway that cancer cells use to grow and multiply. Truqap is typically used in combination with other cancer therapies when the disease has progressed after prior endocrine-based treatment.
Truqap is an AKT inhibitor used to treat certain breast cancers by blocking cancer cell growth pathways.
Key facts at a glance
- RxNorm
- 2669973
- Generic
- Truqap
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Truqap is used to treat hormone receptor-positive (HR+), HER2-negative locally advanced or metastatic breast cancer in adults who have progressed after prior endocrine therapy. It is used in combination with fulvestrant.
Truqap contains capivasertib, which inhibits AKT (protein kinase B), a key enzyme in the PI3K/AKT signaling pathway that cancer cells use for growth, survival, and proliferation.
Common side effects include rash, diarrhea, nausea, fatigue, and hyperglycemia. Truqap may cause serious adverse effects including severe skin reactions. Patients should be monitored for blood glucose and liver function. This medication should not be used during pregnancy. Dosage is typically 400mg taken intermittently (4 days on, 3 days off).
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy