Rituximab
Truxima is a brand-name biosimilar medication referencing Rituxan that works as a CD20-directed cytolytic antibody. It is used to treat certain cancers of the blood and immune system as well as autoimmune conditions by targeting and destroying specific B-cells.
Truxima is a monoclonal antibody biosimilar used to treat certain blood cancers and autoimmune disorders by targeting and eliminating CD20-positive B-cells.
Key facts at a glance
- RxNorm
- 2105827
- Generic
- Truxima
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Truxima treats non-Hodgkin lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, granulomatosis with polyangiitis, microscopic polyangiitis, and pemphigus vulgaris.
As a biosimilar to rituximab, Truxima binds to the CD20 antigen on the surface of B-lymphocytes, triggering immune-mediated destruction of these cells.
Common side effects include infusion reactions, infections, and fatigue. Serious risks include hepatitis B reactivation, progressive multifocal leukoencephalopathy (PML), and cardiac events. Patients should be monitored during and after infusion, and live vaccines should be avoided during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy