Tucatinib
Tukysa (tucatinib) is a targeted cancer therapy known as a HER2 inhibitor used to treat HER2-positive breast cancer. It is prescribed for patients with advanced or metastatic HER2-positive breast cancer who have received prior anti-HER2 therapy, and is typically used in combination with trastuzumab and capecitabine.
Tukysa is a HER2-targeted therapy for advanced HER2-positive breast cancer.
Key facts at a glance
- RxNorm
- 2361291
- Generic
- Tukysa
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Tukysa is indicated for the treatment of adults with HER2-positive advanced or metastatic breast cancer who have received one or more prior anti-HER2-based regimens in the metastatic setting, used in combination with trastuzumab and capecitabine.
Tukysa is an oral tyrosine kinase inhibitor that specifically targets and inhibits the HER2 protein. By blocking HER2 signaling, it helps slow the growth and spread of HER2-positive cancer cells.
Common side effects may include diarrhea, nausea, fatigue, and liver enzyme elevations. Patients should be monitored for liver function during treatment. Tukysa may cause fetal harm and should not be used during pregnancy. Patients should inform their healthcare provider of all medications being taken due to potential drug interactions.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy