Codeine Chlorpheniramine
Tuzistra is a brand-name extended-release cough syrup that combines an opioid cough suppressant with an antihistamine. It is prescribed to provide temporary relief from cough and cold symptoms, particularly those associated with upper respiratory allergies or the common cold.
Tuzistra is a prescription cough medication combining an opioid antitussive with an antihistamine for relief of cough and related cold symptoms.
Key facts at a glance
- RxNorm
- 1652088
- Generic
- Tuzistra
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of cough and upper respiratory symptoms associated with allergies, the common cold, or other respiratory conditions.
Contains codeine, an opioid that suppresses the cough reflex in the brain, combined with chlorpheniramine, an antihistamine that helps reduce nasal congestion and allergic symptoms.
Tuzistra is a prescription-only medication containing an opioid component. It may cause drowsiness and should be used with caution. Codeine carries risks of dependence, and this medication is generally not recommended for children. Patients should avoid alcohol and operating machinery while taking this medication.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy