Tirzepatide
Tyruko is a brand-name biosimilar medication containing natalizumab, used to treat multiple sclerosis and Crohn's disease. It works by preventing certain immune cells from crossing into the brain and intestines, reducing inflammation that causes symptoms in these conditions.
Tyruko is a biosimilar drug used to treat multiple sclerosis and Crohn's disease by reducing harmful inflammation through its action on immune cell migration.
Key facts at a glance
- RxNorm
- 2725175
- Generic
- Tyruko
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Tyruko is FDA-approved for treating adults with relapsing forms of multiple sclerosis (including clinically isolated syndrome, relapsing-remitting, and active secondary progressive disease) and for moderate to severe Crohn's disease in patients who have not responded adequately to other therapies.
Tyruko is a monoclonal antibody that binds to alpha-4 integrin on the surface of immune cells. This prevents these cells from crossing blood vessel walls into the brain and intestines, blocking the inflammatory cascade that causes tissue damage in MS and Crohn's disease.
Tyruko carries a risk of progressive multifocal leukoencephalopathy (PML), a rare but serious brain infection. It is available only through a restricted distribution program requiring regular monitoring. Patients should be screened for JC virus antibodies and monitored for signs of infection and liver problems. Common side effects may include headache, fatigue, joint pain, and increased susceptibility to infections.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy