Ubidecarenone
Ubidecarenone, also known as Coenzyme Q10 (CoQ10), is a naturally occurring compound found in cells that plays a crucial role in energy production within mitochondria. It is primarily used as a complementary therapy for cardiovascular conditions, particularly heart failure, and may be used as a dietary supplement to support overall cardiac function.
Ubidecarenone is a coenzyme used to support heart function and energy production in cells.
Key facts at a glance
- ATC
- C01EB09
- RxNorm
- 21446
- Generic
- Ubidecarenone
- Class
- atc-c01
- Brands
- Chew Q, Q-Gel, Q-Gel with Lipoic Acid, Carni Q-Gel Forte, Liq-10, Q-Up, H2Q, NeoQ10, LiQsorb, QuinZyme, Q-Sorb Co Q-10
- Availability
- otc
- Pregnancy
- N
- Lactation
- caution
- Half-life (h)
- 33
- Onset (min)
- 0
- Duration (h)
- 0
- Routes
- oral
- Forms
- capsule, softgel, tablet, chewable tablet, liquid, gel
- Regions
- United States, European Union, Canada, Australia, Japan, United Kingdom, India
- Monitoring
- INR levels
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 500mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 250mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 400mg daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
8 groupspregnancy
first trimesteruse lowest effective dose if needed
avoid use during pregnancy unless benefits outweigh risks; limited human data available
regular prenatal check-ups
Use with caution and monitor for adverse effects.
pregnancy
second trimesteruse lowest effective dose if needed
avoid unless clearly needed; consult healthcare provider
regular prenatal monitoring
Use with caution and monitor for adverse effects.
pregnancy
third trimesteruse lowest effective dose if needed
avoid close to delivery; discuss with obstetrician
fetal monitoring as prescribed
Use with caution and monitor for adverse effects.
lactation
breastfeedingno specific adjustment
use with caution; CoQ10 naturally present in breast milk but supplemental safety not established
monitor infant for adverse effects
pediatric_age
children 2 12reduce dose based on weight; use pediatric formulation if available
use only under medical supervision for specific conditions like mitochondrial disorders
monitor growth and development
Use with caution and monitor for adverse effects.
geriatric
elderly 65 plusno specific adjustment needed; consider renal/hepatic function
generally well-tolerated; may benefit from supplementation due to natural decline in endogenous CoQ10
periodic monitoring of liver and kidney function
renal_impairment
mild to moderateno dose adjustment required
generally safe; no significant accumulation expected
standard renal function monitoring
hepatic_impairment
mild to moderateno dose adjustment required
generally safe; CoQ10 is not primarily metabolized by liver
periodic liver function tests
Statistics and clinical data
Commonly prescribed since
General prescribing information
Drug class
Drug class information
Common uses
Common therapeutic uses
Used as adjunctive therapy in heart failure management, particularly for patients with chronic heart failure. May also be used for angina, hypertension, and as a dietary supplement for individuals with CoQ10 deficiency. Sometimes prescribed alongside statins to help mitigate statin-induced myopathy.
Ubidecarenone is a fat-soluble compound that participates in the electron transport chain within mitochondria, facilitating the production of adenosine triphosphate (ATP), the primary energy currency of cells. It also acts as an antioxidant, protecting cell membranes from oxidative damage.
Generally well-tolerated with few side effects, though mild gastrointestinal symptoms may occur. May interact with warfarin and certain chemotherapy medications. Patients should consult their healthcare provider before use, particularly if pregnant, breastfeeding, or taking other cardiac medications.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy