Oxymetazoline
Upneeq is a prescription eye drop medication used to treat acquired blepharoptosis (drooping of the upper eyelid) in adults. The medication is an alpha-adrenergic agonist that works by stimulating receptors in the eyelid muscle to help lift the drooping eyelid, improving vision and appearance. It is applied topically to the affected eye(s) once daily.
Prescription eye drops for adults with droopy eyelids that help lift the upper lid by stimulating eyelid muscle receptors.
Key facts at a glance
- RxNorm
- 2391750
- Generic
- Upneeq
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Upneeq is indicated for the treatment of acquired blepharoptosis (acquired ptosis) in adults, a condition where the upper eyelid droops due to weakness in the muscles that lift the eyelid, which can affect vision and cosmetic appearance.
Upneeq contains oxymetazoline, an alpha-adrenergic agonist. When applied topically to the eye, it contracts the Mueller's muscle in the upper eyelid, which helps elevate the eyelid and improve the field of vision.
Upneeq is for prescription use only and should be used exactly as directed by a healthcare provider. Common side effects may include eye redness, eye irritation, or blurred vision. Patients with certain cardiovascular conditions, uncontrolled hypertension, or narrow-angle glaucoma should consult their doctor before use. Do not use if the solution changes color or becomes cloudy.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy