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Ursodeoxycholic Acid

Published: July 26, 2026Updated: August 26, 2026

Urso (ursodiol) is a bile acid medication used to dissolve certain types of gallstones and to treat primary biliary cholangitis, a chronic liver disease. It works by reducing cholesterol production in the liver and increasing bile flow. This medication is typically prescribed when patients are not candidates for surgery or prefer non-surgical treatment options.

Quick summary

Urso is a bile acid medication used to treat gallstones and primary biliary cholangitis by improving bile flow and reducing cholesterol in bile.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 26, 2026Editorial policy

Key facts at a glance

RxNorm
220706
Generic
Urso
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Urso is primarily used to treat primary biliary cholangitis (PBC) and to dissolve cholesterol gallstones in patients who cannot undergo surgery or prefer non-surgical treatment. It may also be used for other liver and bile duct conditions as determined by a healthcare provider.

Urso contains ursodiol, a naturally occurring bile acid that works by decreasing cholesterol production in the liver, increasing bile flow, and replacing toxic bile acids. This helps dissolve cholesterol-based gallstones and protects liver cells from damage.

Urso should be taken with food for best absorption. Patients should have gallstone monitoring every 6 months during treatment. Common side effects may include diarrhea, upset stomach, and nausea. Patients with certain liver conditions, bile duct blockages, or allergies to bile acids should not use this medication. Regular liver function tests are typically required during treatment.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 26, 2026. · Read our editorial policy