Meropenem/Vaborbactam
Vabomere is a brand-name combination antibiotic containing meropenem and vaborbactam, used to treat complicated urinary tract infections (cUTIs) including pyelonephritis in adults. The vaborbactam component helps overcome antibiotic resistance by inhibiting certain beta-lactamase enzymes that would otherwise break down the meropenem component.
Vabomere is an IV antibiotic combination used to treat complicated urinary tract infections by combining meropenem with vaborbactam to overcome resistant bacteria.
Key facts at a glance
- RxNorm
- 1946647
- Generic
- Vabomere
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Vabomere is indicated for treating complicated urinary tract infections (cUTIs), including pyelonephritis, in adult patients caused by susceptible gram-negative bacteria when other antibiotics may not be effective.
Vabomere combines meropenem, a carbapenem antibiotic that kills bacteria by inhibiting cell wall synthesis, with vaborbactam, a beta-lactamase inhibitor that protects meropenem from degradation by KPC-type carbapenemase enzymes, helping overcome antibiotic resistance.
Vabomere is administered intravenously by a healthcare professional. Common side effects include headache, infusion site reactions, and diarrhea. It should be used when other antibiotic options are not appropriate due to its role as a reserved antibiotic. Patients with penicillin allergies may have cross-reactivity concerns.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 29, 2026. · Read our editorial policy