Valchlor
Valchlor (mechlorethamine gel) is a topical prescription medication used to treat early-stage (stage IA and IB) cutaneous T-cell lymphoma (mycosis fungoides-type) in patients who have previously received skin-directed therapy. It is an alkylating agent applied directly to affected areas of the skin.
Valchlor is a topical chemotherapy gel used to treat early-stage cutaneous T-cell lymphoma by applying it directly to skin lesions.
Key facts at a glance
- RxNorm
- 1437556
- Generic
- Valchlor
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Valchlor is indicated for the topical treatment of stage IA and IB mycosis fungoides-type cutaneous T-cell lymphoma in patients who have received prior skin-directed therapy.
Valchlor contains mechlorethamine, an alkylating agent that works by cross-linking DNA in rapidly dividing cells, including abnormal T-cells in the skin, which disrupts their ability to grow and divide.
Valchlor is for topical use only and should be applied only to affected skin areas. Common side effects include skin reactions such as dermatitis, redness, and itching at the application site. Patients should avoid contact with mucous membranes and wash hands after application. The medication may increase the risk of secondary skin cancers with long-term use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy