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Valcyte

Published: July 26, 2026Updated: August 25, 2026

Valcyte (valganciclovir) is an antiviral medication used primarily to treat cytomegalovirus (CMV) infections, particularly in patients with weakened immune systems such as those with HIV/AIDS, organ transplant recipients, or infants born with congenital CMV. It works as a prodrug that converts to ganciclovir in the body to inhibit viral replication.

Quick summary

Valcyte is an antiviral used to treat CMV infections in immunocompromised patients including organ transplant recipients and those with HIV/AIDS.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
304959
Generic
Valcyte
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment and prevention of CMV retinitis in immunocompromised patients, including those with AIDS and organ transplant recipients. Also used for congenital CMV disease in infants.

Valganciclovir is a prodrug that converts to ganciclovir, which inhibits viral DNA polymerase, preventing CMV replication by incorporating into viral DNA and causing chain termination.

Significant toxicity concerns including bone marrow suppression (anemia, neutropenia, thrombocytopenia), nephrotoxicity, and reproductive risks. Requires regular blood monitoring. Should only be used when benefits justify risks, particularly in pregnant women due to teratogenic potential. Available by prescription only.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy