Vamorolone
Vamorolone is a novel dissociative corticosteroid medication designed to treat Duchenne muscular dystrophy (DMD) in patients aged 2 years and older. Unlike traditional corticosteroids, vamorolone works through the glucocorticoid receptor to provide anti-inflammatory and immunosuppressive effects while potentially reducing some of the adverse effects associated with long-term steroid use. It represents an alternative to conventional corticosteroids for managing the inflammatory component of DMD.
Vamorolone is a corticosteroid medication used to treat Duchenne muscular dystrophy by reducing inflammation through glucocorticoid receptor activation.
Key facts at a glance
- ATC
- H02AB18
- RxNorm
- 2669799
- Generic
- Vamorolone
- Class
- atc-h02
- Brands
- Agamree
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- suspension
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Vamorolone is indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients aged 2 years and older. It is used to manage the progressive muscle weakness and inflammation associated with this genetic disorder.
Vamorolone is a dissociative corticosteroid that binds to and activates the glucocorticoid receptor, exerting anti-inflammatory and immunosuppressive effects. While the exact mechanism in DMD is not fully understood, it is believed to reduce muscle inflammation and may help preserve muscle function.
Common side effects may include Cushingoid features, weight gain, and behavioral changes. Vamorolone may affect bone health, growth velocity, and immune function. Regular monitoring of weight, growth, bone density, and adrenal function is recommended during treatment. Patients should not discontinue abruptly without medical supervision due to potential adrenal suppression.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy